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	<title>건강과 대안 &#187; 오진율 40~69%</title>
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		<title>[돼지독감] 신속진단키트 무용지물, 진단적 가치 거의 없어</title>
		<link>http://www.chsc.or.kr/?post_type=reference&#038;p=1058</link>
		<comments>http://www.chsc.or.kr/?post_type=reference&#038;p=1058#comments</comments>
		<pubDate>Fri, 25 Sep 2009 14:13:38 +0000</pubDate>
		<dc:creator>건강과대안</dc:creator>
				<category><![CDATA[식품 · 의약품]]></category>
		<category><![CDATA[H1N1 pandemic]]></category>
		<category><![CDATA[RT-PCR]]></category>
		<category><![CDATA[돼지독감]]></category>
		<category><![CDATA[신속진단키트]]></category>
		<category><![CDATA[신종플루]]></category>
		<category><![CDATA[오진율 40~69%]]></category>

		<guid isPermaLink="false">http://www.chsc.or.kr/?post_type=reference&#038;p=1058</guid>
		<description><![CDATA[미 보건당국에서 RT-PCR을 통해 확정진단을 받은 신종플루 환자의 샘플을 신속진단키트로 실험한 결과 불과 47%에서만 양성이 확인되었다는 소식입니다.앞선 실험에서도 신속진단키트의 오진율이 40~69%에 이른다는 보고가 있었습니다.오진율이 이 정도라면 진단적 가치가 [...]]]></description>
				<content:encoded><![CDATA[<p>미 보건당국에서 RT-PCR을 통해 확정진단을 받은 신종플루 환자의 샘플을 신속진단키트로 실험한 결과 불과 47%에서만 양성이 확인되었다는 소식입니다.<BR><BR>앞선 실험에서도 신속진단키트의 오진율이 40~69%에 이른다는 보고가 있었습니다.<BR><BR>오진율이 이 정도라면 진단적 가치가 전혀 없으며, 신속진단키트를 사용할 필요가 전혀 없다고 생각합니다.<BR><BR>오히려 증상에 따른 처방과 치료를 실시하는 것이 훨씬 효과적이며, 비용부담도 줄일 수 있다고 생각합니다.<BR><BR>=================================<BR><BR>Rapid flu tests miss many swine flu cases: CDC<br />
<DIV class=byline><CITE class=vcard><BR>By Julie Steenhuysen <SPAN class="fn org">Julie Steenhuysen</SPAN> </CITE>– <BR><ABBR class=timedate title=2009-09-24T11:24:22-0700><BR>출처 : Reuters Thu&nbsp;Sep&nbsp;24, 2:24&nbsp;pm&nbsp;ET</ABBR></DIV><!-- end .byline --><br />
<DIV class=yn-story-content><br />
<P>CHICAGO (Reuters) – A study of rapid influenza tests found they miss many cases of swine flu and U.S. health experts said on Thursday they are not worth the trouble for this <SPAN class=yshortcuts id=lw_1253816836_0 style="CURSOR: hand; BORDER-BOTTOM: #0066cc 1px dashed">flu season</SPAN>.</P><br />
<P>A study looking at the effectiveness of a rapid flu test in the first few weeks of the H1N1 <SPAN class=yshortcuts id=lw_1253816836_1 style="CURSOR: hand; BORDER-BOTTOM: #0066cc 1px dashed">pandemic</SPAN> in May found it detected less than half of the cases later confirmed by more sophisticated tests.</P><br />
<P>The findings, which appeared in the <SPAN class=yshortcuts id=lw_1253816836_2>U.S. Centers for Disease Control and Prevention</SPAN>&#8216;s weekly report on death and disease, confirm the <SPAN class=yshortcuts id=lw_1253816836_3 style="CURSOR: hand; BORDER-BOTTOM: #0066cc 1px dashed">CDC</SPAN>&#8216;s current guidelines, which stress that people with flu-like symptoms should get quick treatment, before getting a flu test.</P><br />
<P>Health and Human Services Secretary Kathleen Sebelius told reporters at a briefing that doctors should simply treat symptoms and not bother with testing.</P><br />
<P>&#8220;The flu is the flu is the flu,&#8221; she said.</P><br />
<P>In September, the CDC said doctors should not wait for laboratory confirmation of H1N1 because quick treatment is important, and because a negative rapid test does not rule out the flu.</P><br />
<P>The latest study, conducted by Dr. James Sabetta and colleagues at the Greenwich Hospital and the <SPAN class=yshortcuts id=lw_1253816836_4>Greenwich Department of Health</SPAN> in Connecticut, shows why.</P><br />
<P>They collected data on patients from two school outbreaks of pandemic H1N1 flu in May. They did rapid flu diagnostic tests on 63 patients using the Xpect Flu A&#038;B test by Remel, a unit of <SPAN class=yshortcuts id=lw_1253816836_5>Thermo Fisher Scientific</SPAN>, and more sophisticated lab tests.</P><br />
<P>They found the rapid flu test detected just 47 percent of the <SPAN class=yshortcuts id=lw_1253816836_6>pandemic flu cases</SPAN> later confirmed by a slower, but highly accurate test called real-time reverse transcription-polymerase chain reaction, or rRT-PCR, which checks for the <SPAN class=yshortcuts id=lw_1253816836_7>genetic material</SPAN> of the virus.</P><br />
<P>The findings confirm an earlier study by the CDC that found quick flu tests caught just 40 to 69 percent of swine flu cases. That study, released in August, looked at three popular flu tests &#8212; BinaxNow, made by Inverness Medical Innovations, <SPAN class=yshortcuts id=lw_1253816836_8>Becton Dickinson</SPAN>&#8216;s Directigen EZ Flu A+B test and Quidel&#8217;s QuickVue.</P><br />
<P>The CDC said the findings confirm their current guidelines, and stress that treating flu &#8212; whether seasonal or pandemic &#8212; is more important than knowing what kind a person has.</P><br />
<P>&#8220;Almost everybody will almost certainly not know what kind of flu they had,&#8221; Dr. Anne Schuchat of the CDC told the briefing.</P><br />
<P>Many companies are working on better rapid tests including <SPAN class=yshortcuts id=lw_1253816836_9>GlaxoSmithKline</SPAN> and Enigma Diagnostics, Seegene, a company based in South Korea and Maryland, DxNA based in Utah, and Osmetech PLC, based in California.</P><br />
<P>(Additional reporting by Maggie Fox in Washington)</P><br />
<P></P></DIV></p>
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